Combination pill to help with morning sickness.

Pregvom is a medicine generally prescribed for pregnant women with morning sickness. It contains a combination of two active ingredients— doxylamine and pyridoxine.
Chat with one of our doctors to see if Pregvom is the right choice for you. Order Pregvom online with us and our pharmacy partners will deliver it straight to your doorstep.
Pregvom is a combination of doxylamine and pyridoxine and is used to manage nausea and vomiting during pregnancy (or morning sickness). Doxylamine is an antihistamine that is commonly used to help with symptoms of nausea and vomiting.
Pyridoxine, also known as vitamin B6, is a nutrient that, when combined with doxylamine, can enhance its anti-nausea effects.
Both the active ingredients in Pregvom, doxylamine and pyridoxine, work in different ways to help with morning sickness. Doxylamine helps by blocking certain signals in the brain that trigger nausea and vomiting.
Pyridoxine (vitamin B6), on the other hand, can have a calming effect on your gut. It may reduce gut irritation and overactivity, which can be associated with nausea and vomiting. Pyridoxine also helps with nausea because it is known to regulate serotonin levels in your brain. Serotonin is responsible for mood and nausea regulation, so by maintaining good levels of it, the pyridoxine in Pregvom helps improve your symptoms.
Pregvom comes in a single fixed dose of 10mg doxylamine and 10mg pyridoxine. Your doctor will be able to help you with the exact dosage and for how long to take Pregvom.
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When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy
Here are a few steps to keep in mind when taking Pregvom:
Pregvom is designed to provide gradual and sustained relief, so it may take some time to see the full effect. For some, it might take a week or more of consistent use to start seeing any noticeable difference.
If you have been taking Pregvom as prescribed and do not notice any improvement in your symptoms after a few weeks, consult with your doctor.
If you forget to take your Pregvom pill at the usual time, take it as soon as you remember, unless it's almost time for your next dose. If it's close to the next dose time, just wait and take it then. Don't take two pills together to make up for the one you missed.
If you take too many Pregvom pills by mistake, get help from a doctor right away. To avoid mistakes, you can use a pill organizer or write down when you take your medicine. This can help you remember and reduce errors.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy
Have something specific you want to know about Pregvom? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Organization of Teratology Information Specialists (OTIS); 1994-. Doxylamine succinate-pyridoxine hydrochloride (Diclegis®) 2023 May. Available from:
Effectiveness of delayed-release doxylamine and pyridoxine for nausea and vomiting of pregnancy: a randomized placebo controlled trial. American Journal of Obstetrics and Gynecology, 203(6), pp.571.e1-571.e7
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